Playing flamingo

I’ve been away from the couch for a bit, as I somehow managed to significantly pulverize the bones in my left leg just from falling off a bicycle. I’m home now, trying to figure out how to do everything in a wheelchair with an extended leg brace (the only other option is standing on one leg).

For those interested in the details of my little adventure, I have written a story in the form of a letter to my Aunt Betty:

A little tale of a bicycle… trip

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116 Responses to Playing flamingo

  1. Will says:

    .
    .
    The setting: An indistinct room somewhere in size between an office and a stadium. Walls, partitions, and a sense of… distance. And emptiness. Everything is dark and grey, as if film noir. POV shot. Next to me is a woman who plays the role of a random person selected to stay with a patient while they recover post-op. Poised, soft-spoken, undemanding.

    I appear in my own consciousness mid-scene…

    ————

    This sounds like something out of an Alain Robbe-Grillet novel. If you’ve never read anything by him, it looks like you now might have some time (consider Snapshots, a book of short story vignettes, some of which sound eerily similar to what you wrote above).

    Sorry to hear about your accident Pete. All the cliches come into play, “Take one day at a time”, “Get well soon”, etc. Cliches are cliches for a reason. All the best to you (I’m going to refrain from wishing you a happy Bicycle Day :D). Excellent story by the way…

  2. DdC says:

    CBD and Bone Fracture Healing
    https://www.biotrack.com/cbd-and-bone-fracture-healing-the-best-data-published-for-medical-marijuana-in-fifty-years/
    Scientists in Israel continue to establish their work as the leading source of data on medical cannabis. In a combined study conducted primarily by researchers from Hebrew University of Jerusalem and Tel Aviv University, Cannabidiol (CBD) was found to enhance fracture healing and stimulate Lysyl Hydroxylase (a highly abundant enzyme involved in bone healing) activity in osteoblasts (bone building cells).

    Can Marijuana Help Heal Broken Bones?
    https://www.snopes.com/fact-check/can-marijuana-help-heal-broken-bones/
    A 2008 paper published in Proceedings of the National Academy of Sciences suggested that CBD acted on a previously undescribed endocannabinoid receptor, GPR55, and that this receptor likely plays a role in the regulation of bone mass by inhibiting the growth of cells — osteoclasts — that promote the resorption of bone minerals:

    • DdC says:

      Osteoporosis – Medical Marijuana Research Overview – Medical Marijuana, Inc.
      http://sumo.ly/FSFq
      https://www.medicalmarijuanainc.com/osteoporosis-medical-marijuana-research-overview/
      The cannabinoids found in cannabis have therapeutic potential against osteoporosis because of their interaction with the CB1 and CB2 cannabinoid receptors. They are involved in modulating the bone building and bone resorption functions. Research has found that tetrahydrocannabinol (THC), the major active cannabinoid found in marijuana, activates the CB1 and CB2 cannabinoid receptors.

      Testimonial – CBD for Surgical Scars on Skin
      https://cbdoil.life/blogs/news/testimonial-cbd-for-surgical-scars-on-skin
      “My doctor was AMAZED by how quickly my surgical scars healed using your healing cream. At 2 months he said “Wow you’re way above the curve”! I just had my 6 month checkup yesterday, and he thought it had been a YEAR! Outstanding product!” – Jo Schrubbe

      The Medicine Makers: Choosing Cannabis to Heal Post-Op
      https://cannabisnow.com/using-cannabis-heal-surgery/
      I began my research months ago, asking advice from every person I know who makes their own tinctures and magic potions out of cannabis. The result is a collection of bottles and cans and jars full of pain relieving and anti-inflammatory concoctions which should ease me into a relaxed and healing body.

      Benefits of CBD Oil After Knee Surgery
      https://hempgenix.us/benefits-of-cbd-oil-after-knee-surgery/
      One element that a lot of people are finding a lot of success with reducing inflammation, allowing the body to heal faster and reducing pain is the use of CBD oil after surgery. Research scientists have found that this type of oil is a natural anti-inflammatory and also has antibiotic properties to it as well.

      Cannabis and Hempseed Oil for Post Op Surgical Care
      https://cannabis.net/blog/medical/cannabis-and-hempseed-oil-for-post-op-surgical-care
      Medical Marijuana For Post Surgery Nerve Pain
      https://cannabis.net/blog/medical/cannabis-and-hempseed-oil-for-post-op-surgical-care
      Cannabis is a proven natural remedy for pain caused by almost anything. Its analgesic properties are virtually unmatched in the natural world; no other plant-based medicine works as well as cannabis in alleviating mild to chronic pain.

      But many people still don’t realize that cannabis can also come in handy for nerve damage and pain that occurs after major surgery. Cannabis has been used since ancient times to treat burns and wounds, but it’s still greatly underutilized for its ability to aid in post-operative pain and would healing.

      Using CBD Oil For Healing From Your ACL Surgery
      https://hempgenix.us/using-cbd-oil-for-healing-from-your-acl-surgery/
      Patients using them have a tendency to have faster recoveries and better surgical outcomes compared to patients who do not.

  3. Bruce says:

    Bad Luck eh. Cops impounded my car in Sept. Been on Bicycle all winter. Kindred Spirits eh, sigggh. Prayer Arrrs for you, Pete. Arr. Arr. Amen.

  4. NorCalNative says:

    Pete, best wishes on your recovery and rehab. I’m a fan of pro bicycle racing and the pro’s dread the slow crashes more than high-speed ones.

    I’d put cannabis oil on those scars as frequently as possible. It will help healing and minimize itching. A base of edibles to compliment the opiates, along with toking or vaping as needed would be my recommendation.

    If you read this comment, I’d like more info on the kind of pedals you were using and whether they may have contributed to your fall off the bike.

  5. Servetus says:

    Speaking of CBD for bone healing, the US FDA Center for Drug Evaluation and Research (CDER) Peripheral and Central Nervous System Drugs Advisory Committee (PCNS) has unanimously recommended that cannabidiol receive full FDA approval. An FDA vote is due in June:

    https://www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/PeripheralandCentralNervousSystemDrugsAdvisoryCommittee/UCM604730.pdf

    A commentary on the committee decision at CNN contains a short but excellent video overview of THC biochemistry. It even mentions the entourage effect:

    https://www.cnn.com/2018/04/19/health/fda-committee-marijuana-drug-epilepsy-bn/index.html

    • Pedro says:

      The problem with Epidiolex is that it’s more of a political animal than a medical one.

      With cannabis therapeutics, there’s no one-size-fits-all, medication. Varying ratios of CBD to THC are required to fine-tune seizure reduction. CBD, if it’s going to be on pharmacy shelves should come with several CBD:THC options.

      This will help a small group of patients and leave many potential beneficiaries out. The #1 Rule of Cannabis therapeutics is that there is no such thing as one-size-fits-all.

  6. Deep Dish says:

    4/20 will be a whole month in 2020.

    Happy 4/20, everybody!

  7. darkcycle says:

    …and a happy 4/20 to all my couchmates.
    …P.S. Someone had to:
    That’s not what we mean when we say “Happy bicycle day”, Pete. Get better, man. You need those legs for walking around New York.

  8. FuckedInSpace says:

    Get well, Pete!

  9. primus says:

    My lady friend is a ginger, she tells me that you require more anaesthetic and analgesics than non-gingers. All the best, and happy healing. Maybe now you will have more time for this blog?

  10. Relax and heal, Pete. I wish you well. Save the energy for rehab. With a bit of help from the doctors the body is an amazing healing machine and you’ll be none the worse for wear.

  11. Mike says:

    gee wiz just read your 8 page account,bummer

    would just like to say thank you for all you have
    done to help so many.

    • strayan says:

      Pete, for a long time your blog gave me a reason to get up in the morning.

      I hope you recover in full!

  12. thelbert says:

    you are making me appreciate my good luck, pete. i say, next is another story. you can still write when confined to a chair. i hope IL allows medical herb, for your sake.

  13. claygooding says:

    Happy 420!!

    Green rush hitting (R) party on four fronts. Maher nailed it on his 420 show and told the Democrats how to take Congress back in Nov.

    I hear that train acoming!!!

  14. claygooding says:

    Broke my hip in Aug last year and still walk with hitch in my step but doing fine,,riding scooter again but not planning any trips further than 50 miles. (distance to closest biker bar w/pizza)

    Get well bud,,it’s getting excitng again.

    • Mouthy says:

      Glad you are doing well Mr. Claygooding. I’ll wish you the luck of coming across a pound of gorillaglue on the side of the road.

  15. WalStMonky says:

    .
    .

    Raccoons are one of the most intelligent animals on the planet. But I had no clue that they’ve figured out how to smoke cannabis.

    Pet raccoon smoked too much marijuana, brought to firehouse for help

    /snip/
    The woman was in a panic asking for help, not for herself, but for her pet raccoon.

    The emergency? The raccoon had smoked too much weed and was too stoned to even move.

    “They could tell that the raccoon was lethargic and met all of those symptoms that we typically run into when someone’s been exposed to marijuana,” Pruitt said.

    The firefighters say they felt bad because they love animals, but there wasn’t much they could do for the raccoon except let time take its course.

    They shouldn’t feel badly. They followed the correct treatment protocol to the letter. Also they probably saved the poor woman from getting gouged by a 24 hour veterinarian.

    • DC Reade says:

      A raccoon smoking pot, instead of just using it as an edible? I’ll believe it when I see the vid. A Youtube clip of that would be worth a small fortune.

      • WalStMonky says:

        .
        .

        I was being facetious. I’m all but 100% positive that it was an edible. Do you have any clue of the number of outsiders who believe that combustion is required to gain the benefits of cannabis? Well neither do I but without doubt it’s a huge supermajority of them! So my educated guess is that the firemen in the article were among them.

        I’m not particularly fond of raccoons. The little fuckers were living in the chimney when my wife and I first moved in. It hadn’t rained in about 6 weeks so our newly purchased roof was covered with raccoon turds. They don’t defecate where they sleep you know. We had to shell out almost $500 to get the flues capped or suffer the knowledge that raccoons considered our roof a rest room. How the heck does an animal live in a chimney? Doesn’t the force of gravity make it a pain in the ass to get a good day’s sleep?

  16. Bruce says:

    WordPlay went wierd again, this time we ended up in Budapest.
    Aww man, Beautiful.

    https://traveldigg.com/wp-content/uploads/2016/08/Budapest-At-Night-Aerial-View.jpg

    Uh Ohh, be careful.

    http://webehigh.org/budapest-hungary/

  17. Yeah But says:

    Johann Hari on psychedelics as cure for addiction and depression:
    https://www.alternet.org/are-psychedelics-answer-addiction-and-depression

  18. Servetus says:

    Pete, I hope you’re improving and doing well with your choice of pain meds.

    When I broke my clavicle, I had the opportunity to compare fentanyl and morphine drips at the ER with the gram of aspirin and cannabinoids I consumed prior to my arrival. I wasn’t that impressed with the opiates. For long term pain relief I chose cannabinoids due to the opiate’s chief side effect: constipation. There’s a drug available for opioid constipation, but that was going too far.

    Another good reason to avoid opiates for long term pain relief has just been revealed by Canadian researchers:

    23-APR-2018 — …Recent opioid use is associated with an increased risk of falls in older adults and an increased risk of death, found new research in CMAJ (Canadian Medical Association Journal). […]

    Researchers looked at opioid prescriptions in the preceding 2 weeks before injury and found that the patients who had filled an opioid prescription during this period were 2.4 times more likely to have had a fall causing injury. Patients whose falls were linked to opioid use were also more likely to die during their hospital stay.

    “This study confirms an association between recent opioid use and fall-related injury in a large trauma population of older adults,” writes Dr. Raoul Daoust, Hôpital du Sacré-CÅ“ur de Montréal and the Université de Montréal, Montreal, Quebec, with coauthors. “Physicians should be aware that prescribing opioids to older patients is not only associated with an increased risk of falls, but also, if these patients do fall, a higher in-hospital mortality rate,” conclude the authors. […]

    AAAS Public Release: Recent opioid use and fall-related injury among older patients with trauma

    On a more optimistic note, researchers at the University of Connecticut:

    19-APR-2018…have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

    Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

    To facilitate repair, doctors may install a metal plate to support the bone as it fuses and heals. Yet that can be problematic. Some metals leach ions into surrounding tissue, causing inflammation and irritation. Metals are also very stiff. If a metal plate bears too much load in the leg, the new bone may grow back weaker and be vulnerable to fracture. […]

    In a study recently published in the Journal of the Mechanical Behavior of Biomedical Materials, Wei reports that the high-performance biodegradable composite showed strength and flexibility characteristics that are among the highest ever recorded for similar bioresorbable materials in literature. […]

    “Our results are really high in terms of strength and flexibility, but we feel that if we can get every component to do what we want them to do, we can get even higher,” says Wei, who also serves as the School of Engineering’s associate dean for research and graduate education.

    The new composite is also resilient. Large leg bones in adults and seniors can take many months to heal. The composite developed in Wei’s lab does its job and then starts to degrade after a year. No surgery is required for removal. […]

    AAAS Public Release: Spider silk key to new bone-fixing composite

    Cannabinoids and spider silk; you can’t go wrong.

  19. Dante says:

    Hey Pete;

    So sorry to hear about your mishap (especially since I love to ride my bike).

    Get well soon, and all us folk out here on the inter webs are pulling for you.

  20. Hope says:

    Oh my gosh! I’m so sorry, Pete. Prayers and good vibes. Rest. Study. Heal. Heal well and quickly.

  21. Will says:

    .
    .
    Legal Marijuana’s Big Moment

    https://tinyurl.com/y9xwocpt

    It’s interesting that it’s possible that deal making, one-upmanship, jockeying for position to stay relevant, etc. — instead of a fundamental understanding of the egregious nature of cannabis prohibition in and of itself — might be why laws end up changing at the federal level.

  22. Servetus says:

    The natural wonder otherwise known as the cocoa bean was treated as a controlled substance by the Spanish Inquisition during its 16th century role in the colonialization of Central and South America. By stripping the indigenous population of its traditional natural herbs and medicines, among them cocoa, the Inquisition sought to transform the natives’ social identity and replace it with an identity subservient to the Spanish Christians, thereby enslaving the population to mine gold and silver for their conquistadores.

    Even in its later use by the Spanish, chocolate was suspected of having “moral effects”.

    Today, the veil of superstition lifted a bit as researchers at Loma Linda University Adventist Health Sciences Center announced some of dark chocolate’s (cacao’s) health benefits:

    24-APR-2018 — New research shows there might be health benefits to eating certain types of dark chocolate. Findings from two studies being presented today at the Experimental Biology 2018 annual meeting in San Diego show that consuming dark chocolate that has a high concentration of cacao (minimally 70% cacao, 30% organic cane sugar) has positive effects on stress levels, inflammation, mood, memory and immunity. While it is well known that cacao is a major source of flavonoids, this is the first time the effect has been studied in human subjects to determine how it can support cognitive, endocrine and cardiovascular health.

    Lee S. Berk, DrPH, associate dean of research affairs, School of Allied Health Professions and a researcher in psychoneuroimmunology and food science from Loma Linda University, served as principal investigator on both studies.

    “For years, we have looked at the influence of dark chocolate on neurological functions from the standpoint of sugar content – the more sugar, the happier we are,” Berk said. “This is the first time that we have looked at the impact of large amounts of cacao in doses as small as a regular-sized chocolate bar in humans over short or long periods of time, and are encouraged by the findings. These studies show us that the higher the concentration of cacao, the more positive the impact on cognition, memory, mood, immunity and other beneficial effects.” […]

    AAAS Public Release: New studies show dark chocolate consumption reduces stress and inflammation: Data represent first human trials examining the impact of dark chocolate consumption on cognition and other brain functions

    Moral effects indeed.

  23. DC Reade says:

    Healing furtherance energy to favor your complete recovery, Guither. You’re a national treasure, and one of the reasons we’ve been winning lately.

    Since it sounds as if you’ll have some downtime on your hands, I’d like to recommend a couple of good books:

    Can’t Find My Way Home: America in the Great Stoned Age, 1945-2000, by Martin Torgoff https://www.goodreads.com/book/show/15677197-can-t-find-my-way-home

    and the memoirs of Ulysees S. Grant, which I’m presently reading right now myself. Every bit the classic I’ve been told that it was.

    by the way, I think “mythic insignificance” is a splendid turn of phrase.

  24. kaptinemo says:

    Pete, sorry this is coming late, as I haven’t been ‘here’ in almost two weeks, but I hope you heal up soon. Has electro-stimulation been suggested? You might want to research that.

  25. kaptinemo says:

    Given all that has been said here about drug testing, this will be especially infuriating: This is Why You Can’t Trust “Experts” and Lab Results at Trial by The Daily Bell Staff – April 24, 2018

    from the article:

    A Massachusetts lab technician, Sonja Farak, came to work high every day for 8 years. Well technically, sometimes she arrived sober but was soon high as a kite.

    She worked in a lab that tested drugs confiscated from arrested suspects. Of course, she wasn’t supposed to personally test the drugs… that was what the lab equipment was for.

    In 2014 Farak was sentenced to 18 months in prison and was released in 2015. It took another three years for the courts to toss 11,000 convictions tainted by the worker.

    That is right, the people that Farak helped wrongly convict stayed in prison for another three years after Sonja Farak was released.

    All predictable and predicted, decades ago, when the abominable practice began. For it forgot something ol’ Tom Jefferson warned us about, when he said:

    “In questions of power, then, let no more be heard of confidence in man, but bind him down from mischief by the chains of the Constitution”. http://press-pubs.uchicago.edu/founders/documents/v1ch8s41.html

    Although Jefferson was addressing the mindset behind the ‘Alien and Sedition Laws’, what he had to say is no less applicable to the the DrugWar, because it confers power based upon that ‘confidence in man’ that is so untrustworthy, and this was a perfect example.

    Drug testing has always been an affront to the 4th Amendment; releasing the chains of the Constitution that protected the once inviolable person. Outrages like this, such as the Drugwar has allowed, has caused enormously destructive ‘mischief’ for over 4 decades. ‘Mischief’ such as this perversion of justice.

  26. Servetus says:

    Geneticists have more bad news for prohibs. The prohibitionist assumption that peer influence and/or religious beliefs are exclusive critical factors determining a young person’s drug taking behavior is incorrect. Genes also play a role.

    25-APR-2018 — …Conventional wisdom would argue that part of the reason substance use increases in teens is due to their experiences outside of the home, such as their friends and peers. If they hang out with teens who drink, they will probably drink themselves and vice versa. However, to really understand the importance of external influences like peers, you have to account for the influence of genetic factors.

    Investigators used a unique sample of twins from Quebec who have been followed since birth. Researchers from Florida Atlantic University and collaborators from the University of Montreal, the University of Quebec, and Laval University, in Canada, looked at the relative role of genetics and environment as sources of influence on individual differences in the development of substance use between early adolescence (age 13) and late adolescence (age 17) in 476 twin pairs (475 boys, 477 girls). […]

    …results from the new study show that alcohol and marijuana use increased from early to late adolescence. Genetic as well as shared and non-shared environmental factors explained the amount of substance use; these same factors also partly accounted for inter-individual differences in growth in substance use from ages 13 to 17. Importantly, the researchers’ analyses also revealed genetic influences that are unique to the growth in substance use. With each passing year, genetic differences between individuals become more and more important in explaining why substance use increases in some adolescents but not in others. […]

    AAAS Public Release: Looking past peer influence: Genetic contributions to increases in teen substance use?

    Prohibitionist groups such as those represented by the LDS or Mormon church hierarchy refuse to believe in applied genetics. This is because genetics studies counter Mormon beliefs that Native Americans are descended from the lost tribes of Israel. The true believers will never conclude that changing or restricting people’s drug habits is about as easy as changing the color of people’s eyes. For most Mormons, and many others, the situation will continue to be onward prohibitionist soldiers, marching as to drug war.

  27. Will says:

    .
    .
    Bipartisan Marijuana Speechathon On House Floor

    https://www.marijuanamoment.net/bipartisan-marijuana-speechathon-on-house-floor/

    “As I have said before in this Chamber, Mr. Speaker, the best ally that illegal operators like drug cartels and drug traffickers–who do not pay taxes, who target children, who have no safety standards for their products–the best ally they have are the policies that the Attorney General [Jeff Sessions] has embraced,”[…]

    OUCH! Oh, Jeffy, that really must hurt! Hey Mr. Law & Order, you really are with the criminals. I’d lay low for while, then resign, then slink back to Alabammie…

  28. Servetus says:

    Anti-cannabis propaganda claiming marijuana consumption is an active precursor to psychosis in teenagers received an injection of sanity from researchers in Basel, Switzerland.

    Whereas the mere use of marijuana predicts nothing about future psychoses, using MRI, project leader André Schmidt has uncovered a biomarker that predicts a person’s later development of psychosis with 80 percent accuracy:

    25-APR-2018 — Imaging techniques can be used to detect the development of psychosis in the brains of high-risk patients at an early stage, as reported by researchers from the University of Basel and Western University in the journal JAMA Psychiatry.

    Detecting psychosis early increases the chances of effective treatment. Despite advances in diagnosis, however, it has previously not been possible to examine young people with initial psychotic symptoms and reliably say who will develop acute psychosis and who will not. […]

    The researchers … examined how the folds in various regions of the brain interact with each other, and whether this interaction is impaired in high-risk patients.

    They also tested how precisely they could use the cortical connectivity to predict which high-risk patients would suffer from psychosis and which would not. […]

    “Our results indicate that this type of network analysis could significantly improve individual risk prognoses,” says André Schmidt…. “Future longitudinal studies with larger samples are now needed to validate the prognostic accuracy of this measurement.”

    AAAS Public Release: Indications of psychosis appear in cortical folding

  29. Servetus says:

    It’s not just a problem in the US. Canada is also feeling the effects of opioids:

    AAAS Public Release: One in every six deaths in young adults is opioid-related … opioid-related deaths in Ontario have tripled in past fifteen years, with most significant increase in young adults

    At the Oregon Health & Science University, a new ray of hope for addiction is emerging in hospitals that employ harm reduction techniques and medical science:

    25-APR-2018 — Despite high need, most hospitals lack systems to engage people with substance use disorder, initiate life-saving treatment or connect people to care after hospitalization. This causes tremendous distress among health care providers and patients alike. […]

    “Existing research shows the life-saving benefits of medications for addiction and that most hospitals are not well-prepared to manage complex needs of adults with substance use disorder,” said lead author Honora Englander, M.D., an associate professor of medicine in the OHSU School of Medicine. “Our study shows that not addressing addiction contributes to burnout and frustration among hospital providers. And that by introducing high-quality addiction care, providers feel empowered and relieved. We found that providers’ distress was not inevitable; that by treating people’s addiction not only do we help patients, but we can fundamentally change how providers understand the disease of addiction and change culture.”

    The researchers describes a “sea change” after implementation of a hospital-based addiction medicine team, called the Improving Addiction Care Team, or IMPACT. The study lays out hospital staff perceptions before and after IMPACT, which started at OHSU in 2015, and brings together physicians, social workers, peer-recovery mentors and community providers to tackle the root causes of addiction when patients are admitted to the hospital. […]

    The study concludes that hospital-based interventions for substance use disorder can play a crucial role in addressing the nation’s opioid epidemic.

    “Hospitals need a workforce and systems that can address both the physical and behavioral health needs of this population,” the authors write. “By doing so, hospitals can support staff and reduce burnout, better engage patients, improve care, and reduce stigma from this devastating disease.”

    AAAS Public Release: Hospital staff experience ‘sea change’ in addressing substance use disorder: Providers who participated in study of OHSU initiative to address opioid epidemic express ‘widespread relief’

    Putting hospitals in charge of addiction treatment will completely undermine certain bogus rehab industries.

  30. FuckedInSpace says:

    Michigan approves marijuana legalization vote for November

    It was the second time that the coalition had turned in enough signatures to get on the ballot. The last time, however, it didn’t get the signatures in a state-mandated 180-day window and the petition was thrown out. But the coalition didn’t have the same problem this time around.

    https://tinyurl.com/JiveMoTownJive

  31. WalStMonky says:

    .
    .

    For a while I’ve favored the theory that the powers that be prefer that there be “no way to prove” that a cannabis consumer is “impaired” behind the wheel. The absence of a device to test and establishment of a per se “standard” so that law enforcement can get conviction without the added stress and inconvenience of actually having to prove a driver’s “impairment” is very valuable propaganda. It’s very low maintenance…all they have to do to maintain the status quo is absolutely nothing.

    WSU halts search for marijuana breath test”
    4/27/2018

    /snip/
    The Spokesman-Review reports that Professor Nicholas Lovrich said the project, which began in 2010, ended amid concerns that WSU could lose federal funding under the Trump administration. Attorney General Jeff Sessions rescinded an Obama-era guidance that allowed states to legalize marijuana without federal interference.

    Lovrich says the university denied his proposal for continued research in conjunction with the University of Massachusetts after an assistant attorney general expressed concerns about the university’s liability.

    I can’t for the life of me figure out why the Feds would pull any funding because they’re trying to invent a device that all of the foaming at the mouth prohibitionists swear is desperately needed in the name of highway safety. Perhaps they’re not using ElSohley bunkweed? Also let’s not forget the part where the Feds have never pulled even a penny of funding over this controversy in the more than two DECADES+ since California implemented the Compassionate Use Act in December of 1996.

    • Servetus says:

      The feds can’t do everything, so they rely on the commercial sector or universities to do things for them.

      When the commercial sector examines the economics of cannabis sensors to target motorists in their tracks, much of the technology isn’t there yet, and even if it were there, the ongoing trend toward the acceptance of medical and recreational consumption of cannabis is likely to make a corporation or venture capitalist pause.

      Every year businesses that don’t keep up with science and technology, or in this case politics, succumb to obsolescence. It’s called creative destruction. Companies that fail to prepare themselves for the future end up shutting down. It’s likely from the perspective of many business people cognizant of marijuana politics that investing in prohibition industries is like chaining oneself to the Titanic.

      Former DEA director Karen Tandy (Tandy Co. — Radio Shack) pursued a deal with Motorola to produce pot sensors to test motor vehicle operators. Starting in 2007, Karen Tandy was senior vice president of Public Affairs and Communications for Motorola. Like Radio Shack, the pot sensor project is dead. Motorola lost $4.3 billion from 2007 to 2009, and then restructured its company. In 2016, Karen Tandy joined the Homeland Security Advisory Council where she may be expected to fail once again — this time placing us all in jeopardy.

    • Servetus says:

      I blogged too soon. A new sensor technology developed in China could prove useful for creating a highway breathalyzer for marijuana and other drugs:

      7-MAY-2018 — …A new, low-cost chemical sensing chip brings us one step closer to this technology, which has long been on the wish list of police officers and others looking to monitor drug use and curb dangerous driving.

      The chip could be integrated into a handheld, portable device for detecting drugs in biological samples such as blood, breath, urine or spit.

      “Currently, there is a great demand for on-site drug testing,” says Qiaoqiang Gan, PhD, associate professor of electrical engineering in the University at Buffalo School of Engineering and Applied Sciences. “The high-performance chip we designed was able to detect cocaine within minutes in our experiments. It’s also inexpensive: It can be produced using raw materials that cost around 10 cents, and the fabrication techniques we used are also low-cost.” […]

      The next step in the research is to install the chip in a simple, portable testing device. This technology would first run blood, breath, urine or saliva through a purification process that extracts specific molecules, such as cocaine or other drugs. Then, any chemicals captured through this procedure would be transferred to the chip for detection and identification.

      AAAS Public Release: Chemical sensing chip sniffs out cocaine within minutes – New technology could one day lead to portable drug detectors

  32. tensity1 says:

    A bit late, but as everyone else has said, get well, Pete.

    Be sure to do your therapy, work through the pain. My mother-in-law has two artificial knees, but she didn’t do enough therapy, properly. Because of that, she still has a waddling gait and uses a cane, even though she should be able to walk normally. She is without pain, though. Lesson is, do the therapy–when they tell you, how to, how much, etc. Best wishes.

  33. allan says:

    Ding Dong!

    Personnel note: Calvina Fay to retire from Drug Free America Foundation

    http://floridapolitics.com/archives/262234-personnel-note-calvina-fay

    • The Man Behind the Curtain says:

      .
      .

      Crap, that means that now she’ll be able to spend that much more time practicing her witchcraft. That’s bad news because she is a bad witch. Bad witch!

    • Servetus says:

      No sooner doth one bad witch melt away than another emerges from the depths of darkness and despair to plague our villages and fields with misery and ill fortune. I dare speak of none other than the wicked whacko of Fort Washington, and the Assistant Secretary for Mental Health and Substance Use overseeing the Substance Abuse and Mental Health Services Administration (SAMHSA), Elinore McCance-Katz, MD, PhD.

      Where are all the good witches when you need them?

  34. DdC says:

    I have a curiosity maybe the couch mates can give me some feedback on. I’ve never concerned myself with numbers at tweeter. Most who follow I’ll probably follow at least a while. Basically I post info and not much cat picture socializing. The past few months or so I seem to be garnishing a crowd of Turkish tweeters. All with hundreds of thousands of followers and a few with multi millions. As a realist I find it hard to believe my post are that popular in Turkey. Even with its extensive use of Ganja and draconian punishment. I don’t know enough about hacking or foreign spy crap or so called terrorism. I haven’t seen many post addressing tweets, maybe I’ll just ask them. Just curious. ?

    https://sensiseeds.com/en/blog/cannabis-turkey/

  35. Mike says:

    tonight on CNN at 8pm est.

    Dr Gupta Weed #4 pot or pills

  36. WalStMonky says:

    .
    .

    Well it hasn’t even been a week since the Michigan SoS certified regulated re-legalization for the Election Day 2018 ballot and we’ve already got an opposition group threatening a Federal lawsuit to argue Federal preemption to block the vote from happening argued. It appears that they didn’t bother hiring an attorney because had they done so he would have told them how many times that argument was a loser in the last 2 decades. Nebraska and Oklahoma have been rebuffed twice in Federal Court. Ironically enough, there were at least two attempts in Michigan which got all the way to the SCOTUS. The Roberts Court has simply never had any interest in listening to the incessant whining of the sycophants of prohibition.
    http://healthyandproductivemi.org/

  37. DdC says:

    Justice is what we deserve;
    Mercy is in not getting it.

    Meaning very simply that those presently in power honestly believe themselves to be amongst The Righteous in their Just Crusade against illicit drugs. But like most such crusaders, they tend to forget that what they dismiss as ‘collateral damage’ are not grist for their mills. They are not faceless masses. They are people who live and love, laugh, (and largely due to the efforts of the self-proclaimed moral proctors) cry and suffer.

    But of course, the zealots are doing this out of their sense of tacit moral superiority; only the Just can wield the power of the State to save it…from itself. More correctly, from the perceived barbarians within its’ gates.

    What such people rarely tumble to, until it’s too late for them, is that what they set into motion is very like mounting and riding a tiger. If you get off of it, it will eat you. The actions that the DrugWarriors have set into motion – home invasions, forfeiture, trampling of civil liberties, rending families asunder, and murder(!) of innocents – cannot neatly and quietly be put back into Pandora’s Box without some richly-deserved repercussions.

    They cannot be dismissed without review like the statements of a fantasy prone child. Because, instead of simply case of feelings being hurt, lives have been ruined. Instead of a sand castle being stepped on, people’s homes have been violated. Their careers trashed. And in the case of David Scott, Ismael Mena, Esequiel Hernandez, and God knows how many others, lives have been taken, without even the slightest whiff of due process.

    The more intelligent of them know what’s coming; that is why they are pushing so hard for a de facto police state. You see, they believe that if all of their actions can be sanctioned as legal under the aegis of a police state, they will be safe from the inevitable backlash.

    Yes, they do, indeed, deserve justice. They hunger for it, not realizing it is a two edged sword. The brightest of them know that they will not always be holding it by the haft. Because times *do* change, the circle *does* come round, and the worm *does* turn… sometimes slowly, sometimes in a flash. On the day they learn they are holding it by the edge, they will learn what real pain is. Because after what they have done to me and others, I am not so inclined to be merciful.

    ~ kaptinemo June 02, 2000

    CANNiLIVE @CANNiLIVE
    ☛ HOLD UP….WAIT A MINUTE!
    You mean to tell me that, they’re out here infecting Rats with Cancer & curing them with #Cannabis, but they infect us & our loved ones with Cancer & leave us chopped?!

    ✦ Cannabis Shrinks Tumors: Government Knew in 74 alternet
    ~ DEA shut down cannabis/tumor research
    ~ Ford ended all public research

    ✦ Brain Tumor Patients Dying of Gossip

    I wrote “Pot Shrinks Tumors; Govt. Knew in ’74” back in 2000. Sadly and incredibly, still no substantive human trials 18 years later. Soon, though.
    Howdy Doody @StatesRights420
    Replying to @DendeCannabist @AmeriCannaBlunt

    Until then… Got Ganja?

    ✦ Should it be legalized?
    “soon we will know”
    Life magazine Oct 31, 1969. 25-35

    • Cannabis versus Cancer
      https://blogs.scientificamerican.com/observations/cannabis-versus-cancer/

      “We know weed can mitigate the side effects of the disease and its treatments, but it might also fight malignancies directly”

      “We’re not there yet, but while the available data are limited, research that has been conducted around antitumor effects of cannabinoids so far shows great promise. The International Journal of Oncology published a study last year, for example, indicating that cannabinoids successfully kill cancer cells, and the benefits increase when combined with chemotherapy. An early preclinical study we recently conducted also found that cancer cells derived from patient blood samples were differentially sensitive to the two main active compounds in cannabis—tetrahydrocannabinol (THC) and tetrahydrocannabinolic acid (THCA).”

      “A number of other laboratory and animal studies have been conducted in recent years on colon, breast and brain cancers. They indicate that cannabinoids may inhibit tumor growth by blocking cell growth, causing cell death and blocking the development of blood vessels that tumors require to grow.

      – “We have yet to make the leap to study these promising effects on humans.”

      44 years since this data has been known. 44 years of unaddressed cancer deaths since then. Neglect?
      More like Murder.

    • Servetus says:

      The use of cannabis and its compounds to treat cancer, including any other disease or its symptoms, has historically been thwarted by a therapeutic state that views cannabinoids as personal and social problems — demonic in their origins:

      “The therapeutic state seeks to remedy personal and social problems defined as diseases; its beneficiaries are often ‘helped’ against their will; it is a totalitarian state, governed by the rule of therapeutic discretion.

      ***

      “In the therapeutic state, treatment is contingent on, and justified by, the diagnosis of the patient’s illness and the physician’s prescription of the proper remedy for it… Today, the therapeutic state exercises authority and uses force in the name of health.” The Founding Fathers “could not have anticipated…that an alliance between medicine and the state would then threaten personal liberty and responsibility exactly as they had been threatened by an alliance between church and state.” ~ Dr. Thomas Szasz, The Therapeutic State

      And let’s not forget the state of the therapeutic state in Nazi Germany:

      “The revolution that we have made is a total revolution,” Goebbels stated in November 1933. “It encompasses every aspect of public life from the bottom up. . . . It has completely altered relations between individuals and utterly transformed the relationship between the individual and the state.” The Nazi goal was to “replace individuality with collective racial consciousness and the individual with the community.” In the Third Reich, Goebbels bluntly proclaimed, there would “no longer [be] any free realms in which the individual belongs to himself . . . the time for personal happiness is over.” Or as Robert Ley, minister of Labor, succinctly expressed it, “the individual in Germany who leads a private life is asleep.” […]

      …the Nazis wasted little time in initiating a series of measures aimed at “cleansing the body of the people.” This was to be accomplished by purging “racially inferior” elements from German life—from Jews and Gypsies to the mentally defective, the physically handicapped, and finally to the “socially deviant.” The National Socialist regime viewed itself as a “therapeutic state” that would guarantee public health through racially driven policies of pronatalism, compulsory sterilization, and finally, in 1939, a top secret program of euthanasia.

      — Thomas Childers, The Third Reich: A History of Nazi Germany, 2017, (p. 332, 336). Simon & Schuster. Kindle Edition.

      Cannabis consumption is still considered socially deviant by public figures such as Attorney General Jefferson Beauregard Sessions. Prohibition of cannabis consumption has resulted in phony or ineffective drug rehab programs such as Straight, Narconon, Synanon, and other programs needing to be shut down, just as gay therapy was banned in California. Dismantling the therapeutic state is a key to ending the drug war.

    • kaptinemo says:

      Damn, DdC, you’re making me feel positively ancient.

      And what I said so long ago still stands. The political support for cannabis prohibition is moribund, almost as dead as those who supported it.

      Those replacing them in the electorate are of the generations savaged by the DrugWar and demand its retirement, with only those monetarily benefiting from it fighting a hopeless rearguard. Their tired, shopworn and intellectually insulting protestations against re-legalization are not only falling on deaf ears, but increasingly irritated ones.

      We have the numbers; they have the bureaucracy. But the bureaucracy is changing; it used to be that, in Federal job applications, all (currently) illicit drug use was proscribed.

      Now, you will find on many Federal job applications requiring clearances that if (currently) illicit drugs are being consumed by the applicant, such consumption must not be seen by the public. Obviously they mean primarily cannabis, due to its popularity and increasing re-legalization. Our numbers are causing the once inflexible bureaucracy to bend, slowly, grudgingly, but irresistibly, to our will.

      We reached the tipping point about 9 years ago; it’s all downhill from now on. ‘Social gravity’ will cause the fall to increase in speed, despite the prohib’s efforts to slow it. Their efforts place them directly in the path of the fall, and if they don’t move aside, it will crush them.

      They’ve accumulated a century’s worth of blood karma. They are now grasping the blade of the sword that I mentioned. The haft is sliding into position between our fingers. What we do with it is not up to them, anymore, but up to us.

      And so I end with one observation: as it was said in one of my favorite plays from The Bard, ‘the quality of mercy is not strained’. That is perhaps so, but the amount of mercy dispensed can be measured. And it those who have been harmed the most by the DrugWar who will inevitably do the measuring.

      • DdC says:

        Me too Kapt. I try to remember the earth is spinning faster, we’re not actually getting older. Usually works until my body tells my mind its full of shit. Found it in my net travels and I agree it still applies. Those were the days of searching for stories and dispensaries were unthinkable. Glad we’re still here and able to look back and reminisce. I still remember when Martha (FoM) started Cannabis News. When we would hang out at Cannabis.com and share news and experiences. I do think we’ve come a long way baby. Then we still have a ways to go, so we continue to do what we do to bring truth, justice and the American way. Glad to have known ya Kaptinemo, even gladder we’re on the same side. You’re a powerful weapon I wouldn’t want to face in battle. Proves Prohibitionists are dumb as rocks for trying. Be well.

  38. Servetus says:

    In a Newcastle University study, vapers versus smokers of tobacco have a healthier microbiome. The study’s results may be relevant to various marijuana smokers, as according to another study cigarette smokers are 10 times more likely to be daily marijuana users…[and] among 12 to 17 year olds…are 50 times more likely to be daily cannabis users than non-smokers.

    30-APR-2018 — The first study of its kind has found that people who vape have the same mix of gut bacteria as non-smokers, whilst smokers have significant changes to their microbiome.

    The international team of researchers led by Newcastle University, analysed the bacteria of tobacco smokers, users of e-cigarettes and non-smokers from samples throughout the digestive tract, including in the mouth and gut.

    Significant changes were found in the gut bacteria of the smokers, with an increase in the Prevotella bacteria which is linked to an increased risk of colon cancer and colitis.

    There was also a decrease in the presence of Bacteroides in smokers, a beneficial bacteria or probiotic. A lower level of Bacteroides has been associated with Crohn’s disease and obesity.

    In contrast, the gut flora of those using e-cigarettes was the same as a non-smoker.

    Lead author of the study was Dr Christopher Stewart from the Institute of Cellular Medicine at Newcastle University who published the findings today in PeerJ. He explains: “The bacterial cells in our body outnumber our own human cells and our microbiome weighs more than our brain, yet we are only just beginning to understand its importance on our health. […]

    In the mouth and saliva samples, which are sites directly exposed to the smoke or vapour, the researchers also found that the bacteria in smokers was different to those of the non-smokers. However, like in the gut, the bacteria in the mouth and saliva samples were similar in e-cigarette users and non-smokers. […]

    AAAS Public Release: Vapers and non-smokers have the same flourishing gut flora

    Vaping of cannabinoids preceded tobacco vapes, ushering in a technology that now reveals itself as beneficial for tobacco consumers. It’s one more example of marijuana and its legalization working indirectly to point the way to harm reduction and better health.

    • DdC says:

      Bait and Switch since Vapes are mostly tobacco free and chemical adulterant free. Comparing them to cigarettes with at least 599 chemicals added for pleasure. Same comparison or rather assumption, they tried with cigarettes and Ganja without the chemicals. Ganja is an expectorant producing phlegm to filter the pollutants in the air and in cigarettes. So if someone smokes cigarettes and Ganja they would have cleaner lungs than a cigarette smoker not using. I’m not sure if Vapes produce the same results as Ganja smoke. Without the chemicals they should be cleaner than cigarettes. It would also be logical a non tobacco Vape would be similar to a non smoker bacteria wise. I found using Hemp Oil to help prevent UTI infections and antibiotics for almost 11 years was probably due to getting a fast digesting nutrition to the immune system that gave it fuel to fight off bacteria for the 28 days until a catheter change. More time than that the bacteria would out reproduce the cells fighting it and the growing colony would cause an UTI. So with Ganja supplementing the Endocannabinoid System to balance the gland excretions and other systems. It would likely stimulate the salivary glands if a particulate in the smoke landed on the throat, to trap it from entering the lungs. Whereas cigarettes dry the throat and carcinogens can build on the throat and travel with the air over the dry throat to the lungs. Once again Ganja rules and should be mandatory for cigarette consumption. Which is still used as a mild stress reducer, without the inebriation of drugs or the high with Ganja. I take a couple hits from a Camel straight to relieve coughing from harsh Ganja. It gives me the nicotine fix with less pollutants. I can use one cig for several applications. Thats my story and I’m sticking with it.

      • Servetus says:

        Located at the hash museum in Amsterdam is a little display that explains why it’s so common in Holland to mix marijuana and tobacco if one buys a pre-rolled spliff at the coffeeshops.

        Dutch sailors have been using that particular smoking mix for 500+ years. Based on cancer studies, the marijuana components would have countered tobacco’s carcinogenic tendencies while adding to the overall benefits afforded by smoking weed while being tossed around in a sleeping cubicle by inclement stormy seas. Sea sickness, anyone?

  39. Servetus says:

    Plants. We know them by their names. But how many people actually appreciate the fact that human destiny is inexorably linked to plants?

    30-APR-2018 — Learning how plant cells control the construction of their exterior supports could help scientists devise new ways to either promote the storage of carbon in these structures or facilitate the conversion of carbon-based biomass into biofuels and other useful products.

    The study, published in Nature Plants, reports how two proteins embedded on membranes within plant cells serve as a scaffold to organize three key enzymes that specifically channel carbon into the synthesis of a cell-wall polymer called lignin.

    Lignin is essential to plants’ ability to grow upright and represents a substantial carbon-storage component of plants. But because it surrounds the other cell-wall components–cellulose and hemicellulose–lignin protects these carbon-rich substances from the biochemical processes commonly used to convert them to fuels or other bio-products. Understanding the details of lignin synthesis, in particular, might offer clues about how to conquer this challenge.

    The three enzymes establish the structural characteristics of biochemical building blocks known as monolignols, which link up to form lignin. Scientists previously thought that these enzymes were associated with one another and served as the anchor sites for organizing monolignol synthesis. […]

    AAAS Public Release: New details of molecular machinery that builds plant cell wall components

    Hemp can be used to produce biofuels, a renewable energy that adds nothing to the current levels of C02 in the atmosphere—biobutanols specifically—the technology is available today. And now it’s possible that GMO hemp having bulkier side-walls (more carbon), including other plants genetically modified as such, can be used to produce larger amounts of biofuels at lowered cost, according to Mingyue Gou and CJ Liu at the DoE’s Brookhaven labs. That would make hemp an exit drug for petroleum addiction.

  40. Will says:

    .
    .
    When caving in has nothing to do with doing the right thing, but only a desperate attempt to retain your ‘powerful’ position. I hope she’s voted out anyway;

    Feinstein, facing primary, backs legal weed in California

    http://thehill.com/homenews/senate/385759-feinstein-facing-primary-backs-legal-weed-in-california

    And this bullshit explanation is offered;

    Feinstein’s office told McClatchy that the U.S. senator’s views on marijuana legalization changed after she met with constituents, who voiced having a positive experience with medical marijuana.

    You mean it took 22 years of positive experiences to be described to you Dianne?!

    • WalStMonky says:

      .
      .

      Now, now, it’s easy to miss current events when your head is stuck up your ass.

  41. Will says:

    .
    .
    I wonder how things are going with Corey Gardener’s ‘deal’ with Trump. Meanwhile…;

    The Trump administration has found a new way to crack down on legal weed

    https://tinyurl.com/yavoqaak

    -New rules from the SBA will make it hard for companies that do business with the marijuana industry to gain access to loans.

    -Far from just weed companies, the new rule could extend to web designers, gardening suppliers and others who may derive just a small portion of their revenues from marijuana firms.

    • WalStMonky says:

      .
      .

      At this time pretty much a total non-issue. The financial institutions won’t even give those businesses a friggin’ checking account. Fortunately there’s plenty of private money stepping up to plug the hole.

      • Will says:

        .
        .
        “The financial institutions won’t even give those businesses a friggin’ checking account.”

        You’re missing the point of the article. Previously the only real restrictions were aimed at business that directly ‘touch the plant’. The new SBA rule can now possibly expand beyond direct ‘plant touching’ businesses to so-called ‘indirect’ businesses;

        Under the new rules, even architects, engineers, and your local garden supply company may have to go to alternative sources to get their funding. Alternatively, they may have to turn away a ready source of revenues for providing an otherwise legal
        service or product to a willing buyer in order to comply and gain access to SBA financing.

        I read an article a while back about a small company that made extraction equipment for companies that manufacture essential oils from plants like rosemary, lavender, oregano, etc. The extraction equipment company significantly expanded once cannabis businesses began buying their equipment for the same reasons the essential oils companies did. If they relied on SBA financing to fund their expansion then, they might not be able to do so now — even if they still sell to entirely legal essential oils companies along with state legal/federally illegal cannabis companies.

        • WalStMonky says:

          .
          .

          I didn’t miss anything. The verbiage may have changed but the practical application remains static.

  42. Servetus says:

    The NIDA spent $3 million on a USC study involving “teen tanning addiction”. The NIDA justifies its megabuck funding and its purview by stating that “tanning stimulates the production of endorphins, a natural opioid that improves mood”.

    Cowering to the omnipresent fear Americans might find themselves in a good mood, the NIDA study takes great pains to correlate tanning addiction with marijuana consumption by employing the old scam of guilt-by-association:

    1-MAY-2018 — Tanning addiction plagues teenage minorities in Los Angeles, and that dependency is associated with marijuana abuse, obsessive-compulsive disorder and other mental health issues, a Keck School of Medicine of USC study reports.

    For decades, tanning and tanning addiction was thought to be a problem prevalent almost solely among white, college-age women; however, research by USC’s Kimberly Miller and others are beginning to dispel that myth. […]

    The dangers include melanoma as well as associated negative behaviors and psychological conditions. Teens who reported marijuana use and obsessive-compulsive disorder symptoms were more than twice as likely to meet tanning addiction criteria, the study found.

    Native Hawaiian and Pacific Islanders had the highest prevalence of tanning addiction (10.5 percent) while Asian and Asian-American students had the lowest prevalence of tanning addiction (4.3 percent). […]

    With each additional drug substance used, the likelihood of tanning addiction increased by 67 percent for teenagers, the study reported. And for each additional psychological symptom teens had (panic disorder, bipolar disorder, depression etc.), the likelihood of tanning addiction increased by 30 percent.

    The questions used to determine tanning addiction included:

    ●Have you ever felt you needed to cut down on your tanning?

    ●Have people annoyed you by criticizing your tanning?

    ●Have you ever felt guilty about tanning?

    ●Have you ever felt you needed to tan first thing in the morning?

    AAAS Public Release: Teen tanning addiction afflicts minorities in Los Angeles: USC researchers dispel myth that tanning is a problem only among white, college-age women

    As much as the NIDA wants to spread its net, the hazards of tanning booths are already known. Assuming an actual biological addiction takes place in lieu of something else, such as acculturation, is a bit of a reach—especially when it involves $3-million in funding that would have been better spent had the money been used to justify FDA rescheduling of cannabis and its compounds.

  43. Servetus says:

    A new drug development called JVW-1034 that blocks alcohol withdrawal symptoms and cravings in lab animals may revolutionize treatments for those with alcohol disorders:

    3-MAY-2018 — …If what has been shown to work in worms and rats addicted to alcohol can eventually be demonstrated to work in humans with minimal side effects, it would be a true breakthrough. Scientists point out, however, that the drug has more hoops to go through before that happens.

    There are already drugs on the market prescribed to help people break their addiction to alcohol, but for many patients, they are not very effective and have negative side effects. The new drug, called JVW-1034, targets a different molecular pathway in the body and so far, in animal models, has no obvious side effects.

    “There’s clearly a huge need for something different and better,” said James Sahn, research scientist in chemistry at UT Austin and co-first author of a new paper. “That’s where our approach shines. It’s modulating a pathway that doesn’t seem to be associated with any of the other drugs that are available.” […]

    While the drug is promising, the researchers plan to optimize its chemical properties to have a better chance of being effective in humans. They envision a pill that could one day be taken to block alcohol withdrawal symptoms and cravings, helping people avoid relapsing. But it isn’t clear whether such a drug could actually cure alcoholism. That’s because there are genetic and regulatory underpinnings to the disorder that researchers don’t fully understand yet and that may not be permanently altered by this drug. But even a drug that could be taken chronically or in times of stress could have a huge benefit for people suffering from alcoholism.

    “If we could achieve a medication that is effective for more people and doesn’t have the negative side effects that some of these drugs have, that would be game-changing,” said Martin.

    It might also make a dent in the $250 billion annual cost of alcohol misuse in the U.S., as estimated by a 2015 study. […]

    AAAS Public Release: Anti-alcoholism drug shows promise in animal model

    “Small molecule modulators of σ2R/Tmem97 reduce alcohol withdrawal-induced behaviors”—Louisa L. Scott, James J. Sahn, Antonio Ferragud, Rachel C. Yen, Praveen N. Satarasinghe, Michael D. Wood, Timothy R. Hodges, Ted Shi, Brooke A. Prakash, Kaitlyn M. Friese, Angela Shen, Valentina Sabino, Jonathan T. Pierce & Stephen F. Martin

    Abstract: Neuropsychopharmacology (2018) doi:10.1038/s41386-018-0067-z

  44. Will says:

    .
    .
    Nutty Nora, nuttier than ever;

    Director of drug abuse institute offers words of caution on marijuana

    https://tinyurl.com/y8d3qaof

    • DUH! says:

      Nora on the dangers of legal cannabis:
      “When you legalize, you create an industry whose purpose is to make money selling those drugs.”
      As if that industry didn’t already exist. The harms of prohibition are never addressed by NIDA.

  45. Mike says:

    looks like Dr Guptas Weeds #4 is on at 11pm
    or now

  46. DUH! says:

    More frigging Blue Dogs…. (that and Obama endorsing Feinstein). Why don’t these “Democrats” just piss off and join the party of Trump….
    https://www.huffingtonpost.com/entry/opinion-mcelwee-supreme-court_us_5aeb317ae4b041fd2d23f8db

    • Piss Test Feinstein says:

      Yup, it’s true. The D’s real job is to KILL the hopes and dreams of the political Left.

    • Servetus says:

      Blue, red, purple, it doesn’t matter. Think of drug enforcement as a massive political inquisitor infestation that, like termites, undermines the foundations of governments and people’s lives everywhere.

      Inquisitorial governments are always dysfunctional and corrupt. The instigators do damage to themselves and to others. They create a political system that prevents itself from being found out. The decline and fall of the Spanish Empire was a consequence of its inquisitorial laws and restrictions. Spain lost an 80-year war directed against Dutch heretics–people who smoked hash and smuggled lower-cost Dutch tea into British colonies.

      Direct action (anarchy) enters as one of the few viable remedies against such tyrannies:

      … In the period of agitation and excitement preceding the revolution, there were all sorts and kinds of direct action from the most peaceable to the most violent; and I believe that almost everybody who studies United States history finds the account of these performances the most interesting part of the story, the part which dents into the memory most easily.

      Among the peaceable moves made, were the non-importation agreements, the leagues for wearing homespun clothing and the “committees of correspondence.” As the inevitable growth of hostility progressed, violent direct action developed; e.g., in the matter of destroying the revenue stamps, or the action concerning the [British] tea-ships, either by not permitting the tea to be landed, or by putting it in damp storage, or by throwing it into the harbor, as in Boston, or by compelling a tea-ship owner to set fire to his own ship, as at Annapolis. These are all actions which our commonest textbooks record, certainly not in a condemnatory way, not even in an apologetic way, though they are all cases of direct action against legally constituted authority and property rights. If I draw attention to them, and others of like nature, it is to prove to unreflecting repeaters of words that direct action has always been used, and has the historical sanction of the very people now reprobating it.

      George Washington is said to have been the leader of the Virginia planters’ non-importation league; he would now be “enjoined,” probably by a court, from forming any such league; and if he persisted, he would be fined for contempt. […] — Voltairine de Cleyre (1866-1912); Direct Action by Voltairine De Cleyre

  47. Mike says:

    thought it was for manure or guano

    S ship H high I in T transit

    maybe tea was tagged as well

    —Go Tampa

    https://www.michiganmedicalmarijuana.org/topic/52679-tampa-doctor-uses-medical-marijuana-to-treat-patients-with-autism/?tab=comments#comment-582209

    60 min had good story on how the cost of med is rising

    last Fri night when Dr Gupta was to be on he got premted

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